By Joseph V. Rodricks and Robert G. Tardiff (Eds.)

ISBN-10: 0841208212

ISBN-13: 9780841208216

ISBN-10: 0841210675

ISBN-13: 9780841210677

content material: Conceptual foundation for threat review / Joseph V. Rodricks and Robert G. Tardiff --
Use of toxicity try info within the estimation of hazards to human wellbeing and fitness / Norton Nelson --
Interspecies extrapolation / Daniel B. Menzel and Elaine D. Smolko --
simple suggestions of the dose-response dating / Robert Snyder --
excessive- to low-dose extrapolation in animals / Charles C. Brown --
felony concerns in threat evaluate lower than federal regulatory statutes / Peter Barton Hutt --
Inter-risk comparisons / E.A.C. Crouch and Richard Wilson --
Uncertainty and quantitative review in threat administration / M. Granger Morgan --
Use of chance evaluation and protection assessment / Virgil O. Wodicka --
the necessity for possibility overview of chemical compounds in company choice making / Fred Hoerger --
Chemical views on regulatory impression research / René D. Zentner.

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Lancaster. ; Smith, R. L. Lancet 1977, 2, 584. 20. ; Idle, J. ; Smith, R. L. Xenobiotica 1979, 9, 51. 21. Sloan, T. ; Idle, J. ; Smith, R. L. Br. Med. J. 1978, 2, 655. 22. Idle, J. ; Sloan, T. ; Smith, R. ; Wakile, L. A. Br. J. Pharmacol. 1979, 66, 430. 23. Idle, J. ; Ritchie, J. ; Smith, R. L. Br. J. Pharmacol. 1979,66,432. 24. ; Dring, L. ; Idle, J. ; Smith, R. ; Williams, R. T. Xenobiotica 1979, 9, 397. ; ACS Symposium Series; American Chemical Society: Washington, DC, 1984. 3. MENZEI AND SMOLKO Interspecies Extrapolation 25.

N. W. ; Washington. D. C. Society: 20036Washington, DC, 1984. ACS Symposium Series; American Chemical ASSESSMENT AND MANAGEMENT OF CHEMICAL RISKS L03 Figure 7. Schematic dose-response curve. dose presentation of a log Molar concentration (log) F i g u r e 8. L o g d o s e - r e s p o n s e c u r v e f o r t h e e f f e c t s o f e p i n e p h e r i n e a n d n o r e p i n e p h e r i n e on t h e i s o l a t e d c a t s p l e e n b i o a s s a y system. ( R e p r i n t e d w i t h p e r m i s s i o n from R e f .

ASSESSMENT A N D M A N A G E M E N T OF C H E M I C A L RISKS F i g u r e 1. The r e l a t i o n s h i plotted arithmetically. 5ooor i yui

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Assessment and Management of Chemical Risks by Joseph V. Rodricks and Robert G. Tardiff (Eds.)


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