By Anton Lang (Eds.)

ISBN-10: 0123955416

ISBN-13: 9780123955418

ISBN-10: 0323157718

ISBN-13: 9780323157711

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N e u h a r d (personal communication) has shown t h a t t h e riboside t r i p h o s p h a t e concentrations increase m o r e or less linearly with μ, probably reflecting a parallel increase in t h e r a t e a t which energy is consumed. One of these triphosphates, or a derivative thereof, could therefore be t h e effector we look for. However, I t h i n k this possi­ bility can be excluded, because experiments show t h a t ar can be increased a n d , a t t h e s a m e t i m e , t h e concentrations of all t h e ribo­ side triphosphates drop.

Synthetic peptide models of enzyme active sites. III. Stereoselective esterase models. J. Am. Chem. Soc. 88, 3455-3456. , and SAGAN, C. (1968). " Dell, New York. , and COLE, Μ. N. (1967). Synthesis of biologically pertinent pep­ tides under possible primordial conditions. Proc. Natl. Acad. Sei. U. S. 58, 735-742. , LEMMON, R. , and CALVIN, M. (1965). Dicyandiamide: possible role in peptide synthesis during chemical evolution. Science 147, 1574-1575. , SMITH, A. , and SILVER, J. J. (1968). Synthesis of a sulfur-containing amino acid under simulated prebiotic conditions.

4. GENETIC ANALYSIS W e have seen t h a t a steady state of growth is characterized by an ar value which uniquely defines t h e growth r a t e μ as long as r' r e m a i n s u n c h a n g e d . Schleif originally used an a to indicate t h e frac­ tion of all protein which is ribosomal. In t h e present description of t h e system, I have called this fraction ar, to distinguish it from a general ah where t h e subscript refers to any nonribosomal species of protein in t h e cell. By definition t h e sum of all a values, includ­ ing ar, is unity.

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Communication in Development by Anton Lang (Eds.)


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