By L. David Sibley, Barbara J. Howlett, Joseph Heitman

ISBN-10: 1118038185

ISBN-13: 9781118038185

A distinct and well timed evaluation of the emergence of eukaryotic virulence in fungi, oomycetes, and protozoa, as they impact either animals and plants

Evolution of Virulence in Eukaryotic Microbes addresses new advancements in defining the molecular foundation of virulence in eukaryotic pathogens. by means of analyzing how pathogenic determinants have developed in live performance with their hosts, frequently overcoming innate and adaptive immune mechanisms, the ebook takes a clean examine the selective methods that experience formed their evolution.

Introductory chapters flooring the reader in significant evolutionary subject matters resembling phylogenetics and genetic trade, construction a foundation of information for later chapters masking advances in genetic instruments, how pathogens alternate genetic fabric in nature, and the typical issues of evolutionary variation that result in illness in numerous hosts.

With the objective of linking the examine findings of the various disparate medical groups within the box, the book:

  • Assembles for the 1st time a suite of chapters at the range of eukaryotic microorganisms and the impact of evolutionary forces at the origins and emergence in their virulent attributes
  • Highlights examples from 3 very important, divergent teams of eukaryotic microorganisms that reason sickness in animals and crops: oomycetes, protozoan parasites, and fungi
  • Covers how the improvement of genetic instruments has fostered the id and useful analyses of virulence determinants
  • Addresses how pathogens trade genetic fabric in nature through classical or transformed meiotic tactics, horizontal gene move, and sexual cycles together with those who are cryptic or maybe unisexual
  • Provides a extensive framework for formulating destiny experiences by way of illustrating issues universal to diverse pathogenic microbes

Evolution of Virulence in Eukaryotic Microbes is a perfect booklet for microbiologists, evolutionary biologists and doctors, in addition to graduate scholars, postdoctoral fellows, and college participants engaged on the evolution of pathogens.

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Extra resources for Evolution of Virulence in Eukaryotic Microbes

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LOGSDON, JR. DEFINING SEX “Sex,” in a cellular sense, is surprisingly difficult to define. Is it the act of individuals mating? Is it the occurrence of meiosis? Is it the generation of novel genotypes? These are all components of sexual reproduction, but using any one of them as the sole defining requirement presents problem­ atic exceptions. , 2008). Alternatively, if meiosis is taken as the defining component of sexual reproduction, this definition will include self-fertilization by automixis—a single cell undergoing meiosis with fusion of its progeny gametes to produce genetically novel, albeit (eventually) homozygous individuals (Archetti, *These authors contributed equally to this work.

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Evolution of Virulence in Eukaryotic Microbes by L. David Sibley, Barbara J. Howlett, Joseph Heitman


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