By Engelbert Buxbaum
Textbook for classes at either graduate and undergraduate point. additionally for comparable classes in biochemistry, biochemistry lab, and techniques. includes accomplished analytical description of constitution, biophysics, and serve as of proteins. additionally summarizes the options used to signify protein and protein interactions.
Read or Download Fundamentals of Protein Structure and Function PDF
Similar molecular biology books
This sequence offers studies protecting all features of haemodynamics and haemorheology. issues coated comprise the complexities of microcirculation, the rheology of blood and blood vessels, and the mechanics of blood circulation in arteries and veins. The contributions target to mirror the advances being made in experimental thoughts and instrumentation for laboratory and medical measurements and in numerical and mathematical modelling.
Regardless of the various advances made over the past decade in numerous facets of fungal biochemistry, there were only a few volumes dedicated to the sub ject lately. This lack is all of the extra marvelous in view of the increas ing use of fungi in gene manipulation stories and in biotechnological ap plications, and of the present curiosity within the biorational discovery of novel brokers for the keep an eye on of fungal pathogens of vegetation and people.
Phylogenetic comparative techniques are robust analytical instruments for making evolutionary inferences from interspecific info and phylogenies. The phylogenetic toolkit to be had to evolutionary biologists is at present transforming into at a big pace, yet so much methodological papers are released within the really good statistical literature and lots of are incomprehensible for the person group.
A reference on mobile signaling techniques, the 3rd variation of sign Transduction maintains within the culture of earlier variations, in offering a historic assessment of ways the concept that of stimulus-response coupling arose within the early 20th century and formed our present realizing of the motion of hormones, cytokines, neurotransmitters, development components and adhesion molecules.
- Chloroplasts: current research and future trends
- Kinetics and Mechanism, 3rd Edition
- Signal Transduction Protocols
- Nutrigenomics and Beyond: Informing the Future - Workshop Summary
- Chemistry and Biology
- Computational Molecular Biology
Additional resources for Fundamentals of Protein Structure and Function
The protein structures presented in this book were created with DeepView from data ﬁles obtained from OCA. 4 Quaternary structure Quaternary structure describes how several polypeptide chains come together to form a single functional protein. Like tertiary structure it is determined by ionic and hydrophobic interactions between amino acid R-groups. Many proteins consist of several subunits. Depending on the number of subunits, we speak of monomers, dimers, trimers and so on. Depending on whether these subunits are identical or not, we put homo- or hetero- in front.
E) Multi-domain proteins Folds consisting of two or more domains belonging to diﬀerent classes f) Membrane and cell surface proteins (excluding proteins from the immune system). Usually the transmembrane domains are α-helical, but β-barrels may also occur. g) Small proteins Usually dominated by metal ligand, haeme, and/or disulphide bridges h) coiled coil proteins α-helices wound around each other. 7. Examples for α, β, α/β and α + β protein structures. There are two images for each protein (right and left eye view) to achieve a stereo eﬀect.
A comparison of structures determined by the two methods shows fortunately that they are fairly similar, giving us faith in both. Computer predictions The biggest problem for the determination of protein structure is the vast amount of highly puriﬁed protein required (≈ 100 mg) for any of the above 22 2 Protein structure methods. Many proteins of particular biological interest occur in very small amounts in our body. In the last 20 years the sequences of many proteins have been determined by DNA sequencing (an almost complete sequence of the human genome was published in 2001 [16, 17, 78]).
Fundamentals of Protein Structure and Function by Engelbert Buxbaum