By Susan Aldridge

ISBN-10: 0511001304

ISBN-13: 9780511001307

ISBN-10: 0521584140

ISBN-13: 9780521584142

Now we have all been drug clients at one time or one other. medicines can be utilized as medications, as foodstuff ingredients, for excitement, and to guard our long term well-being. With such a lot of new medicines out there and an ever-widening definition of what precisely makes a drug a drug, we must always all be good trained in regards to the medications we use--how they paintings, their advantages, and their hazards. This e-book is a special consultant for the final reader to the medicine of daily life--from as a rule prescribed medicinal drugs to leisure medicines (including illicit ones) and nutrients vitamins. the writer examines how medicines have interaction with their objectives within the physique, the place medicines come from, how they're built, and what new types of medications are at the horizon. She stories all of the significant pharmaceutical medicines--painkillers, antibiotics, anti-cancer medicines, anti-depressants, middle medicines, tranquilizers, and hormones. even more than a shopper instruction manual, this quantity conveys the attention-grabbing technological know-how in the back of medications in an simply obtainable approach.

Show description

Read Online or Download Magic Molecules: How Drugs Work PDF

Similar molecular biology books

Read e-book online Advances in Hemodynamics and Hemorheology PDF

This sequence provides experiences masking all points of haemodynamics and haemorheology. themes coated comprise the complexities of microcirculation, the rheology of blood and blood vessels, and the mechanics of blood stream in arteries and veins. The contributions goal to mirror the advances being made in experimental recommendations and instrumentation for laboratory and scientific measurements and in numerical and mathematical modelling.

Download e-book for kindle: Biochemistry of Cell Walls and Membranes in Fungi by Paul J. Kuhn, Anthony P.J. Trinci, Michel J. Jung, Michael

Regardless of the numerous advances made over the past decade in a variety of elements of fungal biochemistry, there were only a few volumes dedicated to the sub­ ject lately. This lack is all of the extra spectacular in view of the increas­ ing use of fungi in gene manipulation experiences and in biotechnological ap­ plications, and of the present curiosity within the biorational discovery of novel brokers for the regulate of fungal pathogens of crops and people.

Modern Phylogenetic Comparative Methods and Their by László Zsolt Garamszegi PDF

Phylogenetic comparative techniques are robust analytical instruments for making evolutionary inferences from interspecific information and phylogenies. The phylogenetic toolkit to be had to evolutionary biologists is at present turning out to be at an immense velocity, yet such a lot methodological papers are released within the really good statistical literature and lots of are incomprehensible for the consumer neighborhood.

Signal Transduction, Third Edition by Ijsbrand M. Kramer PDF

A reference on mobile signaling approaches, the 3rd variation of sign Transduction maintains within the culture of earlier versions, in offering a old assessment of the way the idea that of stimulus-response coupling arose within the early 20th century and formed our present knowing of the motion of hormones, cytokines, neurotransmitters, progress components and adhesion molecules.

Extra info for Magic Molecules: How Drugs Work

Sample text

More often, though, drugs interact to give an adverse effect. Nearly half of hospital patients take six or more drugs. The number of possible interactions between the drugs increases steeply with the number of drugs prescribed. If someone is on two drugs there can only be one interaction between them. If they are taking seven, then there are 21 possible interactions. Minimising drugdrug interactions is where the skill of the prescriber is really tested. For example, they will know that a drug with a narrow therapeutic index like the heart drug digoxin is more sensitive to any second drug that enhances its effect.

Largish molecules such as the antibiotic cefotaxime, which is used in the treatment of meningitis, cannot easily penetrate the walls of the small intestine. Typically less than 20 per cent of a dose of cefotaxime, and related antibiotics, ends up in the circulation. Other drugs such as the anti-depressants imipramine and doxepin run into trouble when they get to the liver, which breaks down more than half of the molecules in the given dose. A drug's ability to negotiate the gut and liver is known as its bioavailability.

The interaction tends to tip the digoxin over into its toxic range. The patient may well start to suffer side effects when a second or subsequent drug is added to their programme. Removing, replacing or reducing the dose of the interacting drug may well eliminate the side effects. A good understanding of how each drug acts in the body means that most drug interactions are predictable although there is always the odd surprise. So, if two drugs have similar effects, their effects will be additive.

Download PDF sample

Magic Molecules: How Drugs Work by Susan Aldridge

by Charles

Rated 4.06 of 5 – based on 3 votes