By James D. Watson, Tania A. Baker, Stephen P. Bell, Alexander Gann, Michael Levine, Richard Losick
Now thoroughly updated with the newest learn advances, the Seventh variation of James D. Watson’s vintage e-book, Molecular Biology of the Gene retains the certain personality of past variations that has made it the main usual e-book in molecular biology. Twenty-two concise chapters, co-authored through six hugely individual biologists, supply present, authoritative insurance of an exhilarating, fast-changing discipline.
Read Online or Download Molecular Biology of the Gene (7th Edition) PDF
Best molecular biology books
This sequence offers studies overlaying all points of haemodynamics and haemorheology. issues coated comprise the complexities of microcirculation, the rheology of blood and blood vessels, and the mechanics of blood movement in arteries and veins. The contributions target to mirror the advances being made in experimental ideas and instrumentation for laboratory and scientific measurements and in numerical and mathematical modelling.
Regardless of the various advances made over the last decade in numerous points of fungal biochemistry, there were only a few volumes dedicated to the sub ject lately. This lack is the entire extra superb in view of the increas ing use of fungi in gene manipulation reviews and in biotechnological ap plications, and of the present curiosity within the biorational discovery of novel brokers for the regulate of fungal pathogens of vegetation and people.
Phylogenetic comparative methods are strong analytical instruments for making evolutionary inferences from interspecific facts and phylogenies. The phylogenetic toolkit on hand to evolutionary biologists is at present turning out to be at a big pace, yet such a lot methodological papers are released within the really good statistical literature and plenty of are incomprehensible for the person group.
A reference on mobile signaling strategies, the 3rd variation of sign Transduction maintains within the culture of past versions, in delivering a historic assessment of the way the idea that of stimulus-response coupling arose within the early 20th century and formed our present knowing of the motion of hormones, cytokines, neurotransmitters, progress components and adhesion molecules.
- Physical Biology of the Cell
- Elastomeric Proteins: Structures, Biomechanical Properties, and Biological Roles
- Cell Cycle Control: Mechanisms and Protocols
- Progress in Nucleic Acid Research and Molecular Biology, Vol. 53
Additional resources for Molecular Biology of the Gene (7th Edition)
One obvious hypothesis states that genes can change (mutate) to give rise to new genes (mutant genes). This hypothesis was ﬁrst seriously tested, beginning in 1908, by the great American biologist Thomas Hunt Morgan and his young collaborators, geneticists Calvin B. Bridges, Hermann J. Muller, and Alfred H. Sturtevant. They worked with the tiny ﬂy Drosophila melanogaster. The ﬁrst mutant found was a male with white eyes instead of the normal red eyes. The white-eyed variant appeared spontaneously in a a parental generation red & culture bottle of red-eyed ﬂies.
When these experiments were carried to a third (F3) progeny generation, all the F2 peas with recessive traits bred true ( produced progeny with the recessive traits). Those with dominant traits fell into two groups: one third bred true ( produced only progeny with the dominant trait); the remaining two-thirds again produced mixed progeny in a 3:1 ratio of dominant to recessive. Mendel correctly interpreted his results as follows (Fig. 1-1): the various traits are controlled by pairs of factors (which we now call genes), one factor derived from the male parent, the other from the female.
The Mendelian View of the World parental generation 1-3 How Mendel’s second law (independent assortment) operates. In this example, the inheritance of yellow (Y ) and green ( y) seed color is followed together with the inheritance of round (R) and wrinkled (r) seed shapes. The R and Y alleles are dominant over r and y. The genotypes of the various parents and progeny are indicated by letter combinations, and four different phenotypes are distinguished by appropriate shading. FIGURE × rryy RRYY RY gametes ry F1 generation RrYy RY Ry F2 generation gametes Ry rY ry RRYy RrYy Ry RRYY RrYY RrYy ry RrYY RrYy rrYY rrYy gametes rY RRYy RRyy Rryy ry RY RY gametes rY 9 RrYy Rryy rrYy rryy GENE LINKAGE AND CROSSING OVER Mendel’s principle of independent assortment is based on the fact that genes located on different chromosomes behave independently during meiosis.
Molecular Biology of the Gene (7th Edition) by James D. Watson, Tania A. Baker, Stephen P. Bell, Alexander Gann, Michael Levine, Richard Losick